• Home
  • Research
  • Gestational Diabetes

Gestational Diabetes

Gestational diabetes, what is it?

Gestational diabetes has been a concern for over 50 years but the proposal of new international screening criteria only found a consensus of opinion after the publication of the results of the HAPO (Hyperglycaemia and Adverse Pregnancy Outcome) study in 2008. This study confirmed the existence of a constant relationship between the mother’s glycaemia and maternal and foetal morbidity. In 2010, different French medical associations (SNGOF, SFD and SFP) established a framework and in 2014 pregnant women were discussed during an SFD congress, demonstrating the willingness to put forward leads to respond to this complex issue. We now know that gestational diabetes is a conducive factor for the appearance of Type 2 diabetes in the longer term and that its treatment and intensive monitoring protect against certain mother to child complications in the short term. On the other hand, we lack crucial data on the impact of treatments prescribed during pregnancy and on the subsequent life of the mother and child.

Our Strategy

A combination of clinical research and basic and applied research, in order to better understand the mechanisms of gestational diabetes and the transmission of metabolic imprinting to descendants and the predisposition to develop obesity and/or diabetes.

Results of the in vivo study

Oxidative stress and gestational diabetes: A new avenue of research

Clinical studies on obese women developing gestational diabetes have shown an increase of oxidative stress that is explained by a sideration of antioxidant capabilities. Thanks to the mouse model, we were able to demonstrate the importance of oxidative stress in gestational diabetes and its complications

Read more

Clinical research project: Gestational diabetes, oxidative stress and metformin

Since 2012, CEED participates in an inter-regional Regional Clinical Research Programme, whose objective is to compare the effects of several treatments on patients with gestational diabetes:

Read more

Our partners

Our Sponsors