À propos de BIETIGER William

Présentation

Suite à l’obtention d’un BTS en biotechnologie, William Bietiger a intégré le CEED en 2007 au poste de technicien de laboratoire. Après 3 années passées à se perfectionner sur les différentes techniques utilisées, il a pu devenir technicien référent en 2010. Avec l’expérience il a présenté une VAE obtenu en 2014 qui lui a permis d’obtenir le poste d’ingénieur d’étude. Il a pour mission le management de l’équipe technique ainsi que la mise au point et l’optimisation des techniques utilisées sur les différentes thématiques de recherche.

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Principales publications

Beta-Cell-Specific Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 5 Aggravates High-Fat Diet-Induced Impairment of Islet Insulin Secretion in Mice

Oral insulin delivery, the challenge to increase insulin bioavailability: influence of surface charge in nanoparticle system

Treatment of NASH with Antioxidant Therapy: Beneficial Effect of Red Cabbage on Type 2 Diabetic Rats.

Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats.

Improvement of islet graft function using liraglutide: anti-inflammatory properties

High-fructose and high-fat diet-induced disorders: Impact on diabetes risk, and hepatic and vascular complications

Impact of the route of insulin administration on metabolism in a diabetic rat model

Impact of an autologous oxygenating matrix culture system on rat islet transplantation outcome.

Portal or subcutaneous insulin infusion: efficacy and impact on liver inflammation.

Design, characterisation, and bioefficiency of insulin-chitosan nanoparticles after stabilisation by freeze-drying or cross-linking.

Oxidative stress status and liver tissue defences in diabetic rats during intensive subcutaneous insulin therapy.

Oxidative stress type influences the properties of antioxidants containing polyphenols in RINm5Fbeta cells

In vitro and in vivo investigation of the angiogenic effects of liraglutide during islet transplantation

Impact of pancreatic rat islet density on cell survival during hypoxia.

Metabolic and oxidative stress markers in Wistar rats after 2 months on a high-fat diet.

Pro-inflammatory and pro-oxidant status of pancreatic islet in vitro is controlled by TLR-4 and HO-1 pathways.

Apport de l’insulinothérapie par voie intrapéritonéale : impacts sur le stress oxydant et le diabète.

Perfluorocarbon emulsions prevent hypoxia of pancreatic β-cells.

Improvement of rat islet viability during transplantation: validation of pharmacological approach to induce VEGF overexpression.

Duodenum-specific drug delivery: in vivo assessment of a pharmaceutically developed enteric-coated capsule for a broad applicability in rat studies.

Instant blood-mediated inflammatory reaction during islet transplantation: the role of Toll-like receptors signaling pathways.

Role of islet culture on angiogenic and inflammatory mechanisms.

Adenoviral infection or deferoxamine? Two approaches to overexpress VEGF in beta-cell lines.

Extracellular matrix proteins involved in pseudoislets formation.

Overexpression of vascular endothelial growth factor in vitro using deferoxamine: a new drug to increase islet vascularization during transplantation.